This justifies the claims made regarding the use of the oleo gum resin of Gardenia lucida in CNS disorders. The essential oil of the oleo gum resin of Gardenia lucida is a CNS depressant and anticonvulsant with central muscle relaxant properties. A significant decrease in locomotion, motor impairment and loss of gripping reflex was also observed. The oil significantly potentiated the barbitone induced hypnosis and offered significant protection against the intensity and frequency of convulsions and mortality rate in both the convulsant models. Effect on motor activity was evaluated using an actophotometer, rotarod and grip strength methods. The hypnotic and anticonvulsant activity was assessed by pentobarbitone induced hypnosis and convulsant models-Maximum electroshock (MES) and Pentylene tetrazole (PTZ) respectively. The essential oil isolated from it was screened for CNS activities to check if it is responsible for the claims made regarding the traditional use of the oleo gum resin. The oleo gum resin of Gardenia lucida is commonly employed in traditional medicine to treat multiple ailments, including epilepsy and mania. Shareef, Mohammad Zubair Yellu, Narsimha Reddy Achanta, Venkata Narsimha Appa Rao Neuropharmacological screening of essential oil from oleo gum resin of Gardenia lucida Roxb. On the other hand, the oleo gels studied present low values of the friction coefficient obtained in a tribological contact, although only some GMS/castor oil-based oleo gels exhibit a suitable mechanical stability. The rheological behavior of SMS-based oleo gels also depends on the cooling rate applied during the gelification process. The use of low-viscosity oils, such as rapeseed and soybean oils, yields gels with significantly higher values of the linear viscoelastic functions than oleo gels prepared with high-viscosity oils, i.e. Glyceryl monostearate (GMS) generally produces stronger gels than sorbitan monostearate (SMS). SAOS response and mechanical stability of these oleo gels are significantly influenced by the type and concentration of the organogelator and the vegetable oil used in the formulations. In particular, the rheological behavior, by means of small-amplitude oscillatory shear (SAOS) measurements, and some lubrication performance-related properties (mechanical stability and tribological response) have been evaluated in this work. Oleo gels based on sorbitan and glyceryl mono stearates and different types of vegetable oils, potentially applicable as biodegradable alternatives to traditional lubricating greases, have been studied. Rheology of oleo gels based on sorbitan and glyceryl mono stearates and vegetable oils for lubricating applicationsĮnergy Technology Data Exchange (ETDEWEB)
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